Riyadi Adrizain1, Dyah Ayu Shinta Lesmanawati2, Fadila Dyah Trie Utami1 , Anggraini Alam1 and Djatnika Setiabudi1
Affiliations
1Department of Child Health, Faculty of Medicine, Universitas Padjadjaran/Hasan Sadikin General Hospital, Bandung, West Java, Indonesia 2 Pediatric Resident, Department of Child Health, Faculty of Medicine, Universitas Padjadjaran/Hasan Sadikin General Hospital, Bandung, West Java, Indonesia
Background
• MIS-C is a rare but serious complication of COVID-19 that weakens children’s immune systems, increasing susceptibility to secondary infections such as tuberculosis (TB).
• This case highlights a 15-year-old girl with MIS-C complicated by severe TB and other conditions.
Methods
• The patient presented with respiratory failure, increased intracranial pressure with status epilepticus, TB meningitis, severe dengue, disseminated TB, anti-TB drug-induced hepatotoxicity, and cutaneous drug eruption following a prior COVID-19 infection.
• A multidisciplinary team (respirology, cardiology, pediatric neurology, immunology, gastro-hepatology) managed her care.
Key Results
• She received high-dose steroids, an anti-tuberculosis regimen, phenobarbital for seizure control, N-acetylcysteine, and enoxaparin.
• She was discharged after three weeks of intensive care but required recurring monthly readmissions due to complications.
Discussion & Conclusion
• This case underscores the importance of early detection and comprehensive, multidisciplinary management of MIS-C.
• Such management can reduce mortality risk and long-term complications from secondary infections like TB.
Related SDGs
SDG 3: Good Health and Well-Being – strengthens clinical understanding of managing complex pediatric infectious complications, supporting better child health outcomes.
Journal Information
Journal: BMC Infectious Diseases
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