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Managing concurrent nephrotic syndrome, spontaneous bacterial peritonitis, and herpes zoster in an immunocompromised child: Diagnostic difficulties and treatment outcomes

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Authors

Riyadi Adrizain a,*69946c28 40eb 44f4 a6b1 ac6e6f16c28d, Ismiana Modjaningrat c, Winyarti c, Fadila Dyah Trie Utami a, Wilson Surya Lesmana d, Vita Indriasari b, Dedi Rachmadi Sjambas a

Affiliations

a Department of Child Health, Faculty of Medicine, Universitas Padjadjaran/Hasan Sadikin General Hospital, Bandung, West Java, Indonesia b Pediatric Surgery Division, Department of Surgery, Faculty of Medicine, Universitas Padjadjaran/Hasan Sadikin General Hospital, Bandung, West Java, Indonesia c Pediatric Resident, Department of Child Health, Faculty of Medicine, Universitas Padjadjaran/Hasan Sadikin General Hospital, Bandung, West Java, Indonesia d Pediatric Surgery Resident, Department of Surgery, Faculty of Medicine, Universitas Padjadjaran/Hasan Sadikin General Hospital, Bandung, West Java, Indonesia

Background

• Nephrotic syndrome (NS) involves heavy protein loss in urine, and poorly controlled disease can lead to serious infectious complications.

• Immunocompromised children with NS face added risk from opportunistic infections.

Methods

• Case report of a 9-year-old boy with a history of nephrotic syndrome since age 7, poorly controlled due to irregular medication use.

• He presented with worsening abdominal pain, fever, and facial oedema, and was managed through hospitalization with imaging, lavage drainage, and antibiotic therapy.

Key Results

• The patient was diagnosed with spontaneous bacterial peritonitis and septic shock related to uncontrolled nephrotic syndrome.

• During hospitalization he developed herpes zoster skin lesions linked to his immunocompromised state.

• He improved with antibiotics and supportive care and was discharged with outpatient follow-up.

Discussion & Conclusion

• This case highlights the importance of early, aggressive intervention in immunocompromised children with nephrotic syndrome facing multiple infectious complications.

• Regular medication adherence is critical to preventing this kind of double infectious burden.

Related SDGs

SDG 3: Good Health and Well-Being – Improving care for children with complex kidney disease

Journal Information

Journal: Idcases

DOI: https://doi.org/10.1016/j.idcr.2026.e02489

gita sonia

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