Authors
Auda Nadira ^1,3, Sunita Sunita ^3,4,6, Bima Diokta Alparisi^3,7, Amanda Cheryl Fayza^3,5, Nur Syifa Rahmatika^1,3, Putri Karisa^3,4, Nova Sylviana^2,3 and Mas Rizky A.A Syamsunarno^2,3

Affiliations

¹Master Study Program of Biomedical Sciences, Faculty of Medicine, Universitas Padjadjaran, Bandung, West Java, Indonesia

²Department of Biomedical Sciences, Faculty of Medicine Universitas Padjadjaran, Bandung, West Java, Indonesia

³Cardiometabolic Working Group Study, Faculty of Medicine, Universitas Padjadjaran, Bandung, West Java, Indonesia

⁴Doctoral Program, Faculty of Medicine, Universitas Padjadjaran, Bandung, West Java, Indonesia

⁵Bachelor Study Program, Faculty of Medicine, Universitas Padjadjaran, Bandung, West Java, Indonesia

⁶Department of Medical Laboratory Technology, Poltekkes Kemenkes Bengkulu, Bengkulu, Indonesia

⁷Clinical Professional Program, RSUD Arifin Achmad, Faculty of Medicine, Universitas Riau, Pekanbaru, Riau, Indonesia

Background

• Major adverse cardiovascular events (MACE) remain a leading cause of poor prognosis after acute myocardial infarction (AMI).

• Adipokines from fat tissue may add cardiometabolic risk information beyond conventional measures.

Methods

• Systematic review and meta-analysis of adiponectin and visfatin levels in adult AMI patients with and without MACE.

• Five cohort studies (707 patients) from China, Taiwan, Japan, and Poland were included.

Key Results

• Adiponectin levels were lower in patients who had MACE.

• Visfatin levels were significantly higher in the MACE group.

Discussion & Conclusion

• Lower adiponectin and higher visfatin are associated with MACE after AMI.

• BMI did not show significant discriminatory value.

Related SDGs

SDG 3: Good Health and Well-Being – Improving risk prediction after heart attack

Journal Information

Journal: BMC Cardiovascular Disorders

DOI: https://doi.org/10.1186/s12872-026-06120-0