Human papillomavirus (HPV) is most commonly associated with genital warts, but a study by Universitas Padjadjaran dermatologists has shown how the virus can appear in unusual ways, especially in people with weakened immune systems. Led by Dr. Pati Aji Achdiat of the Faculty of Medicine, the team reported a case of an HIV-positive patient whose hand and foot warts were caused by HPV type 6—a strain typically linked to genital infections.

The patient, struggling with HIV-related immune suppression, developed widespread verruca vulgaris (common warts). When the lesions were tested, doctors were surprised to find HPV type 6 present in the skin of the hands and feet, an atypical finding rarely documented before. This case highlights how immunocompromised individuals may show unusual disease patterns, making diagnosis and treatment more complex.

While warts may seem minor, in immunosuppressed patients they can cause pain, secondary infections, and social stigma. The discovery of genital-associated HPV outside its usual site also raises new questions for clinicians. Should routine HPV testing expand to cover more body sites in HIV patients? Could this knowledge help prevent further complications?

The case underscores the importance of personalized care for patients living with HIV. By recognizing unusual presentations of infections, doctors can adapt their diagnostic approach and ensure timely intervention. This is especially relevant in Indonesia, where access to comprehensive HIV care remains uneven.

Universitas Padjadjaran’s contribution here is both scientific and human-centered, reminding us that viruses adapt in surprising ways, and so must medical practice. It directly supports SDG 3: Good Health and Well-Being, while demonstrating the university’s role in strengthening clinical understanding worldwide.